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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T67935 | Tubulin inhibitor 11 | Apoptosis , Microtubule Associated | |
Tubulin Inhibitor 11 is a potent, orally active agent that inhibits tubulin by targeting the Colchicine binding site. It impedes tubulin polymerization, leading to mitotic blockade and apoptosis. | |||
T13225 | Tubulin inhibitor 7 | Microtubule Associated | |
Tubulin inhibitor 7 is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines (tubulin polymerization (IC50: 0.52 μM), K562 cell growth (IC50: 11 nM)). | |||
T10640 | C-11 | Others | |
C-11 is a tubulin inhibitor and acts as an ADC cytotoxin with cytotoxicity for carcinoma cell lines. | |||
T62498 | Tubulin polymerization-IN-20 | ||
Tubulin aggregation-IN-20 (compound 11) is a potent tubulin aggregation inhibitor. tubulin aggregation-IN-20 has the potential to be investigated in breast and drug-resistant colon cancer. | |||
T79206 | MC-EVCit-PAB-MMAE | ||
MC-EVCit-PAB-MMAE (Linker-Payload 11), a conjugate utilized in antibody-drug conjugates (ADCs), comprises the MC-EVCit-PAB linker attached to the powerful tubulin polymerization inhibitor MMAE [1]. |